Prospects for Stimulating Autoimmunity and Developing New T Cells in Cancer Treatment

Abstract

Any adverse problem or weakening of the body's immunity, such as HIV infection, long-term physical and mental stress, nutritional deficiencies, chemotherapy or major surgery, will make cells prone to cancer. The body's immune system also deteriorates with age, which may help understand how people's risk of developing cancer increases significantly as they age. If the body's immune system is no longer strong enough to completely destroy cancer cells, then we move from "eliminating" cancer to "balancing."The immune system is the body's protective network, consisting of immune cells, immune organs, and immune substances. It fights against foreign pathogens and mutated cells in the body to maintain the health of the human body's internal environment.

Strictly speaking, patients with better physical conditions have higher and more powerful T cells, and the more T cells awakened by immune drugs, they are relatively more effective in eliminating tumor cells. Currently, T cell-based immunotherapy includes CAR-T therapy, TCR-T therapy, TILs therapy, and CTL therapy.