Potential carcinogenic mechanism of hepatitis B virus X protein (HBX) mediated by microRNA (miRNA)

Abstract

The hepatocellular carcinoma (HCC) is the sixth most common cancer in the world. The hepatitis B virus (HBV) is crucial in the growth of HCC. Hepatitis B virus X protein (HBX) has been linked in numerous studies to the clinical prognosis of patients with hepatocellular carcinoma, but the exact mechanism is still unknown. Short non-coding RNAs identified as miRNAs have a significant influence in many malignancies. Numerous research conducted recently have discovered a strong connection between HBX and miRNA. In order to offer thoughts on the diagnosis and care of people with advanced hepatocellular carcinoma who have hepatitis B virus infection, this article examines recent study findings.